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National Videos
May 31, 2022
New Delhi, May 31 (ANI): According to the University of Texas MD Anderson Cancer Center, researchers have developed an ultrasound-guided cancer immunotherapy platform that promotes systemic anti-tumour immunity and increases immune checkpoint blockade therapeutic efficacy. The findings of the research were published in the journal ‘Nature Nanotechnology’. As the first-of-its-kind platform, the Microbubble-assisted UltraSound-guided Immunotherapy of Cancer (MUSIC) approach employs nano complexes combined with microbubbles to effectively deliver cyclic guanosine monophosphate-adenosine monophosphate (cGAMP), an immuno-transmitter involved in anti-cancer immunity, into antigen-presenting cells (APCs). Inside the APCs, the microbubbles release cGAMP to activate the GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway, which stimulates type I interferon responses that are essential for priming tumour-specific T cells. In the preclinical study, the MUSIC strategy demonstrated a complete tumour eradication rate of 60 per cent when administered as monotherapy in breast cancer models. When combined with an anti-PD-1 antibody, MUSIC significantly improved anti-tumour responses with minimal toxicity effects, including enhanced primary tumour control and decreased systemic disease progression. In addition, the combination therapy demonstrated superior survival benefit, with a 76 per cent increase in median survival compared to either therapy alone.
Congress wanted candidate from its party for RS polls: Jharkhand AICC In-charge Avinash Pande
Ranchi (Jharkhand), May 31 (ANI): While speaking on the Rajya Sabha (RS) candidate announced by the Jharkhand Mukti Morcha (JMM), Jharkhand All India Congress Committee (AICC)...
‘New history of Champawat will be created’, assures CM Dhami to voters
Champawat (Uttarakhand), May 31, (ANI): Uttarakhand Chief Minister Pushkar Singh Dhami on May 31 visited at Banbasa polling centre in Champawat. The Chief Minister is contesting...
Garbage being cleared at Kedarnath Dham after PM Modi’s appeal in ‘Mann Ki Baat’
Rudraprayag (Uttarakhand), May 31 (ANI): The garbage spread in Kedarnath Shrine and its surrounding areas is now getting cleared. After the appeal of the Prime Minister,...
Huge crowd gathers outside Sidhu Moose Wala’s home to get last glimpseHuge crowd gathers outside Sidhu Moose Wala’s home to get last glimpse
Mansa (Punjab), May 31 (ANI): Huge crowd gathered outside slain singer Sidhu Moose Wala’s house as his body was brought home from Mansa Civil Hospital on...
Himachal Pradesh welcomes PM Modi
Shimla (Himachal Pradesh), May 31 (ANI): Prime Minister Narendra Modi visited Shimla, Himachal Pradesh on May 31 to participate in the 'Garib Kalyan Sammelan' and release...
COVID: India records 2,338 new cases, 19 deaths in last 24 hours
New Delhi, May 31 (ANI): India reported 2,338 new cases of COVID-19, 2,134 recoveries, and 19 deaths in the last 24 hours. The active caseload currently...
Preparations in full swing to welcome PM Modi in Himachal Pradesh
Shimla (Himachal Pradesh), May 31 (ANI): Ahead of Prime Minister Narendra Modi's visit to Himachal Pradesh, preparations are in full swing to welcome him. Arrangements have...
Uttarakhand: Voting begins for Chmapawat By-poll
Champawat (Uttarakhand), May 31, (ANI): The voting for the Champawat By-election has begun at 7 am on May 31. People queued up at the Banbasa polling...
Odisha: Polling begins for Brajrajnagar By-poll amid tight security
Jharsuguda (Odisha), May 31 (ANI): Polling for the Brajarajnagar Assembly Constituency By-poll in Odisha has begun on May 31. The fate of 11 candidates are in...
CM Dhami offers prayers at a temple in Khatima ahead of voting for Champawat By-poll
Khatima (Uttarakhand), May 31 (ANI): Uttarakhand Chief Minister Pushkar Singh Dhami offered prayers at a temple in Kahtima on May 31 ahead of voting for Champawat...
RCP Singh takes dig at Nitish Kumar a day after not being fielded for RS polls
Patna (Bihar), May 31 (ANI): A day after the Janata Dal (United) decided against nominating Union steel minister RCP Singh for the Rajya Sabha elections, the...
AAP MP Sanjay Singh blames BJP for arrest of Satyendar Jain
New Delhi, May 31 (ANI): After ED arrested Delhi’s Health Minister Satyendar Jain in a case connected to hawala transactions related to a Kolkata-based company, Aam...
